Abstract Search

ea0089c5 | Clinical – Chemo/SSA/Biologics | NANETS2022

c-MET Expression in MEN1-associated Neuroendocrine Tumors

MD Raisa Ghosh , BS Maya Lee , BS Rana Tora , MGC, CGC James Welch , I Vaishali , BS Parekh , MD Jaydira del Rivero , F William , MD Simonds , MD Lee Scott Weinstein , E Jenny , MD Blau , K Sunita , Ph.D Agarwal , MD Smita Jha

Background: Multiple studies have shown that approximately 50-70% of patients with MEN1 die of causes directly related to MEN1 particularly gastroenteropancreatic (GEP) neuroendocrine tumors (NETs). While non-functional GEP-NETs are the most common in the general population, gastrinomas (40%) are the most common functional GEP-NETs in patients with MEN1. c-Met is a proto-oncogene that encodes for c-MET, a tyrosine kinase receptor which promotes tumor cell motility, proliferati...

0 shares

Endocrine Abstracts

c-MET Expression in MEN1-associated Neuroendocrine Tumors

BiosciAbstracts